Bone has the ability to regenerate as part of the healing process after an injury, as well as during skeletal development and ongoing remodelling throughout adulthood. In order to optimize skeletal repair and restore skeletal function, bone regeneration is composed of a well-orchestrated series of biological events of bone induction and conduction, involving a variety of cell types and intracellular and extracellular molecular-signaling pathways, with a definable temporal and spatial sequence, involving a number of cell types and intracellular and extracellular molecular-signalling pathways. The most common form of bone regeneration in the clinical context is fracture healing, which mimics the normal embryonic skeletogenesis pathway, including intramembranous and endochondral ossification. Bone tissue engineering (BTE) has been around for about three decades. The BTE discipline has witnessed enormous growth in interest and progress over the years, with an exponentially increasing number of papers and reviews published. BTE is a field that focuses on alternative therapy methods that, in theory, will eliminate the previously mentioned difficulties with currently employed clinical therapies (i.e., donor site morbidity, limited availability, immune rejection, and pathogen transfer). To attain the ultimate aim of developing bone grafts that improve bone repair and regeneration, BTE requires the collaboration of scientists, engineers, and surgeons.
Title : Small activating RNA from concept to phase 2 clinical trials
Nagy Habib, MiNA Therapeutics Ltd, United Kingdom
Title : Mechanical modulation of cell response in 3D bioprinted hydrogels
Ruben F Pereira, University of Porto, Portugal
Title : Electroactive polymer-based smart scaffolds for tissue engineering and regenerative medicine
Federico Carpi, University of Florence, Italy
Title : Graphene “Hastalex®”, butterfly, and stem cells are set to revolutionise the development of human organs.
Alexander Seifalian, NanoRegMed Ltd, BioScience Innovation Centre, United Kingdom
Title : Design of 3D bioengineered personalized scaffolds to potentiate bone ingrowth and angiogenic network for oral tissues reconstruction
Christiane Salgado , Institute of Research and Innovation in Health(i3S), Brazil
Title : RADA16-I based scaffolds for wound healing and regenerative medicine
Deptula Milena, Medical University of Gdansk, Poland