Bone has the ability to regenerate as part of the healing process after an injury, as well as during skeletal development and ongoing remodelling throughout adulthood. In order to optimize skeletal repair and restore skeletal function, bone regeneration is composed of a well-orchestrated series of biological events of bone induction and conduction, involving a variety of cell types and intracellular and extracellular molecular-signaling pathways, with a definable temporal and spatial sequence, involving a number of cell types and intracellular and extracellular molecular-signalling pathways. The most common form of bone regeneration in the clinical context is fracture healing, which mimics the normal embryonic skeletogenesis pathway, including intramembranous and endochondral ossification. Bone tissue engineering (BTE) has been around for about three decades. The BTE discipline has witnessed enormous growth in interest and progress over the years, with an exponentially increasing number of papers and reviews published. BTE is a field that focuses on alternative therapy methods that, in theory, will eliminate the previously mentioned difficulties with currently employed clinical therapies (i.e., donor site morbidity, limited availability, immune rejection, and pathogen transfer). To attain the ultimate aim of developing bone grafts that improve bone repair and regeneration, BTE requires the collaboration of scientists, engineers, and surgeons.
Title : Side effect free cancer chemotherapy by directed gene delivery using nanomaterials
A C Matin, Stanford University School of Medicine, United States
Title : Artificial intelligence (AI) in biomedical engineering
Hossein Hosseinkhani, Innovation Center for Advanced Technology, Matrix HT, United States
Title : Novel gene therapy options for pulmonary hypertension
Yong Xiao Wang, Albany Medical College, United States
Title : Challenges in skeletal tissue engineering
Patrizia Ferretti, UCL Great Ormond Street Institute of Child Health, United Kingdom
Title : Electroactive polymer-based smart scaffolds for tissue engineering and regenerative medicine
Federico Carpi, University of Florence, Italy
Title : Remote activation of mechanotransduction via integrin alpha-5 by aptamer conjugated magnetic nanoparticles promotes osteogenesis
Hadi Hajiali, University of Birmingham, United Kingdom