Bone has the ability to regenerate as part of the healing process after an injury, as well as during skeletal development and ongoing remodelling throughout adulthood. In order to optimize skeletal repair and restore skeletal function, bone regeneration is composed of a well-orchestrated series of biological events of bone induction and conduction, involving a variety of cell types and intracellular and extracellular molecular-signaling pathways, with a definable temporal and spatial sequence, involving a number of cell types and intracellular and extracellular molecular-signalling pathways. The most common form of bone regeneration in the clinical context is fracture healing, which mimics the normal embryonic skeletogenesis pathway, including intramembranous and endochondral ossification. Bone tissue engineering (BTE) has been around for about three decades. The BTE discipline has witnessed enormous growth in interest and progress over the years, with an exponentially increasing number of papers and reviews published. BTE is a field that focuses on alternative therapy methods that, in theory, will eliminate the previously mentioned difficulties with currently employed clinical therapies (i.e., donor site morbidity, limited availability, immune rejection, and pathogen transfer). To attain the ultimate aim of developing bone grafts that improve bone repair and regeneration, BTE requires the collaboration of scientists, engineers, and surgeons.
Title : A revolution or surrender: The success and failures of tissue engineering and regenerative medicine
Thomas J Webster, Hebei University of Technology, United States
Title : Efficacy and safety outcomes in patients with chronic traumatic brain injury: Final analysis of the randomized, double-blind, surgical sham-controlled phase 2 STEMTRA trial
Bijan Nejadnik, SanBio, Inc, United States
Title : Light-based bioprinting: From bioink design to modulation of cell response in bioprinted hydrogels
Ruben F Pereira, University of Porto, Portugal
Title : Biofabrication of functional human intestinal tissue with villi and crypts using high-resolution 3D printing technique
Lindy Jang, Lawrence Livermore National Laboratory, United States
Title : Embracing the potential of biopolymer based hydrogel: The new frontier in chronic wound therapy
Madhu Gupta, School of Pharmaceutical Sciences, India
Title : A 3D -bioprinted in vitro adipose tissue model for the study of macrophage polarisation and function within metabolic disease.
Tiah Oates, University of Bristol, United Kingdom