Gene Editing is a revolutionary molecular technology that enables precise modifications to an organism's DNA. The most widely used and influential gene editing technique is CRISPR-Cas9, which utilizes a bacterial enzyme, Cas9, guided by RNA molecules to target and cut specific DNA sequences. This cut triggers the cellular repair machinery, allowing the introduction of desired genetic alterations. Gene editing holds immense potential for both basic research and therapeutic applications. In research, it facilitates the study of gene function, regulation, and the development of various organisms. In medicine, gene editing offers unprecedented possibilities for treating genetic disorders by correcting or modifying faulty genes. Promising applications include the potential cure of genetic diseases, such as sickle cell anemia and cystic fibrosis. Moreover, gene editing has implications in agriculture, as it allows for the development of crops with improved traits, increased resistance to pests, and enhanced nutritional content. Ethical concerns, such as the unintended consequences of editing the human germline and the potential for designer babies, have prompted ethical discussions and calls for responsible use. Despite challenges, gene editing continues to be at the forefront of scientific advancements, paving the way for transformative breakthroughs in diverse fields. Ongoing research aims to refine techniques, address ethical considerations, and unlock the full potential of gene editing in shaping the future of biology, medicine, and agriculture.
Title : AI-integrated high-throughput tissue-chip for space-based biomanufacturing applications
Kunal Mitra, Florida Tech, United States
Title : Will be updated soon...
Vasiliki E Kalodimou, European University-Cyprus Ltd, Cyprus
Title : Will be updated soon...
Nagy Habib, Imperial College London, United Kingdom
Title : Will be updated soon...
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, United Kingdom
Title : Advanced 3D tissue models: Pioneering tools for investigating health and disease
Lucie Bacakova, Institute of Physiology of the Czech Academy of Sciences, Czech Republic
Title : Developing iPSC-derived 3D Outer Blood-Retinal Barrier Disease Models of Choroideremia for Gene Therapy Evaluation
Aradhana Kasimsetty, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), United States