Gene Editing is a revolutionary molecular technology that enables precise modifications to an organism's DNA. The most widely used and influential gene editing technique is CRISPR-Cas9, which utilizes a bacterial enzyme, Cas9, guided by RNA molecules to target and cut specific DNA sequences. This cut triggers the cellular repair machinery, allowing the introduction of desired genetic alterations. Gene editing holds immense potential for both basic research and therapeutic applications. In research, it facilitates the study of gene function, regulation, and the development of various organisms. In medicine, gene editing offers unprecedented possibilities for treating genetic disorders by correcting or modifying faulty genes. Promising applications include the potential cure of genetic diseases, such as sickle cell anemia and cystic fibrosis. Moreover, gene editing has implications in agriculture, as it allows for the development of crops with improved traits, increased resistance to pests, and enhanced nutritional content. Ethical concerns, such as the unintended consequences of editing the human germline and the potential for designer babies, have prompted ethical discussions and calls for responsible use. Despite challenges, gene editing continues to be at the forefront of scientific advancements, paving the way for transformative breakthroughs in diverse fields. Ongoing research aims to refine techniques, address ethical considerations, and unlock the full potential of gene editing in shaping the future of biology, medicine, and agriculture.
Title : AI-integrated high-throughput tissue-chip for space-based biomanufacturing applications
Kunal Mitra, Florida Tech, United States
Title : Stem cell technologies to integrate biodesign related tissue engineering within the frame of cell based regenerative medicine: towards the preventive therapeutic and rehabilitative resources and benefits
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : In vitro evaluation of lyophilized Dedifferentiated Fat cells (DFAT) impregnated artificial dermis
Kazutaka Soejima, Nihon University, School of Medicine, Japan
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Nagy Habib, Imperial College London, United Kingdom
Title :
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, United Kingdom
Title : The regenerative medicine of the future
Marco Polettini, DVM, Italy