Tissue engineering scaffolds strive to create biophysical and chemical signals that resemble the stem cell environment. Stem cells, on the other hand, may detect these features and alter their fate. Scientists use scaffold design and in vitro studies to try to explain these events, but the mechanisms involved are still unknown. Mechanical forces in cell behaviour, in particular, have only recently begun to gain attention. Mechanical stress, for example, can cause cell deformation and remodelling, which has a substantial impact on cellular function. Living cells also sustain or create forces, and mechanical loading causes deformation and remodelling, which has an impact on many aspects of human health and disease. As a result, stress in cell behaviour has received increased attention. It's difficult to model the constitutive behaviour of cells using biophysical cues. The stimuli are present in vivo, but reproducing their features in vitro is a difficulty.
Title : Eliminating implants infections with nanomedicine: Human results
Thomas J Webster, Interstellar Therapeutics, United States
Title : Graphene, butterfly structures, and stem cells: A revolution in surgical implants
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, London NW1 0NH, United Kingdom
Title : Biodistribution and gene targeting in regenerative medicine
Nagy Habib, Imperial College London, United Kingdom
Title : Precision in cartilage repair: Breakthroughs in biofabrication process optimization
Pedro Morouco, Polytechnic of Leiria, Portugal
Title : AI-integrated high-throughput tissue-chip for brain aging
Kunal Mitra, Florida Tech, United States
Title : Assembly and stability of on-chip microvasculature
Kara E McCloskey, University of California, Merced, United States