Tissue engineering scaffolds strive to create biophysical and chemical signals that resemble the stem cell environment. Stem cells, on the other hand, may detect these features and alter their fate. Scientists use scaffold design and in vitro studies to try to explain these events, but the mechanisms involved are still unknown. Mechanical forces in cell behaviour, in particular, have only recently begun to gain attention. Mechanical stress, for example, can cause cell deformation and remodelling, which has a substantial impact on cellular function. Living cells also sustain or create forces, and mechanical loading causes deformation and remodelling, which has an impact on many aspects of human health and disease. As a result, stress in cell behaviour has received increased attention. It's difficult to model the constitutive behaviour of cells using biophysical cues. The stimuli are present in vivo, but reproducing their features in vitro is a difficulty.
Title : A revolution or surrender: The success and failures of tissue engineering and regenerative medicine
Thomas J Webster, Hebei University of Technology, United States
Title : Efficacy and safety outcomes in patients with chronic traumatic brain injury: Final analysis of the randomized, double-blind, surgical sham-controlled phase 2 STEMTRA trial
Bijan Nejadnik, SanBio, Inc, United States
Title : Light-based bioprinting: From bioink design to modulation of cell response in bioprinted hydrogels
Ruben F Pereira, University of Porto, Portugal
Title : Biofabrication of functional human intestinal tissue with villi and crypts using high-resolution 3D printing technique
Lindy Jang, Lawrence Livermore National Laboratory, United States
Title : Embracing the potential of biopolymer based hydrogel: The new frontier in chronic wound therapy
Madhu Gupta, School of Pharmaceutical Sciences, India
Title : A 3D -bioprinted in vitro adipose tissue model for the study of macrophage polarisation and function within metabolic disease.
Tiah Oates, University of Bristol, United Kingdom