Neurogenesis refers to the process by which new neurons, the basic building blocks of the nervous system, are generated from neural stem cells or progenitor cells. While traditionally believed to occur primarily during embryonic development, contemporary research has demonstrated that neurogenesis persists throughout adulthood, particularly in specific regions of the brain, such as the hippocampus and the olfactory bulb. In the adult brain, neural stem cells located in specialized niches undergo division and differentiation, giving rise to new neurons. This phenomenon is associated with cognitive functions, learning, and memory. Neurotrophic factors, environmental stimuli, and physical activity have been identified as factors influencing the rate of neurogenesis. Understanding neurogenesis is crucial for unraveling the complexities of brain plasticity, adaptation, and repair. It has implications for cognitive health, mood regulation, and recovery from neurological injuries or diseases. Conversely, deficits in neurogenesis have been linked to various psychiatric and neurodegenerative disorders. Research in neurogenesis encompasses molecular, cellular, and behavioral aspects. Advanced imaging techniques, molecular biology tools, and animal models are employed to explore the mechanisms underlying the birth, migration, and integration of new neurons into existing neural circuits. Manipulating neurogenesis holds therapeutic potential for conditions like depression, anxiety, and neurodegenerative diseases. While challenges remain in fully harnessing the regenerative capacity of the adult brain, ongoing studies continue to shed light on the intricacies of neurogenesis, offering hope for innovative treatments and interventions in neurological and psychiatric disorders.
Title : AI-integrated high-throughput tissue-chip for space-based biomanufacturing applications
Kunal Mitra, Florida Tech, United States
Title : Stem cell technologies to integrate biodesign related tissue engineering within the frame of cell based regenerative medicine: towards the preventive therapeutic and rehabilitative resources and benefits
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : In vitro evaluation of lyophilized Dedifferentiated Fat cells (DFAT) impregnated artificial dermis
Kazutaka Soejima, Nihon University, School of Medicine, Japan
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Nagy Habib, Imperial College London, United Kingdom
Title :
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, United Kingdom
Title : The regenerative medicine of the future
Marco Polettini, DVM, Italy