Bioengineering a living tissue is a fascinating procedure that could help us live longer and more fulfilling lives by providing "spare parts" for damaged or diseased tissues. Furthermore, the set of tools being developed by tissue engineers has the potential to completely transform the way we do biological investigations and eliminate the need for animal testing. Tissue engineering has progressed from its origins in the creation of tissue replacements to contemporary efforts in the creation of human tissues for regenerative medicine and mechanistic investigations of tissue illness, injury, and regeneration. Major advancements in the subject have been made possible by advances in bioengineering, material science, and stem cell biology. The ultimate goal of three-dimensional bioprinting is to create person-specific, defect-site specific constructions by designing and developing functioning anatomically relevant human tissues/organs to replace diseased, damaged tissues/organs. Organoid formation using self-assembled embryonic stem cells has been recognized as one of the most important in vitro approaches for producing mini organs such as mini-guts, brain-like organoids, and liver organoids. Tissue engineers' main task is to create clinically meaningful, patient-specific structures. Scaffold serves as a structural template for cell attachment and tissue growth, as well as providing numerous cues to cells that regulate gene expression and protein creation. Bioreactors are essential for maintaining the precise culture conditions required for cell proliferation and differentiation, such as pH, osmolality, temperature, and oxygen concentration.
Title : A revolution or surrender: The success and failures of tissue engineering and regenerative medicine
Thomas J Webster, Hebei University of Technology, United States
Title : Efficacy and safety outcomes in patients with chronic traumatic brain injury: Final analysis of the randomized, double-blind, surgical sham-controlled phase 2 STEMTRA trial
Bijan Nejadnik, SanBio, Inc, United States
Title : Light-based bioprinting: From bioink design to modulation of cell response in bioprinted hydrogels
Ruben F Pereira, University of Porto, Portugal
Title : Biofabrication of functional human intestinal tissue with villi and crypts using high-resolution 3D printing technique
Lindy Jang, Lawrence Livermore National Laboratory, United States
Title : Embracing the potential of biopolymer based hydrogel: The new frontier in chronic wound therapy
Madhu Gupta, School of Pharmaceutical Sciences, India
Title : A 3D -bioprinted in vitro adipose tissue model for the study of macrophage polarisation and function within metabolic disease.
Tiah Oates, University of Bristol, United Kingdom