Scaffolds are made of biodegradable materials in tissue engineering to enable tissue growth, ECM elaboration, and the final maturation or conversion of the implanted construct into functional, native tissue. The remodelling process is dynamic and complex, reliant on factors such as the host implant location, inflammatory response, mechanical environment, and disease status, to name a few. Despite the complexity of the problem, scaffold design principles allow some general alternatives in terms of chemistry and processing to regulate degradation, provided there is enough in vivo data to guide such design improvements. Non-invasive and non-destructive imaging technologies to examine implants in situ in a timely manner are crucial with the rapid expansion of biomaterial discovery and associated efforts to bring such discoveries into the clinic. Structure, mechanical, and biological changes such as scaffold degradation, mechanical strength, cell infiltration, extracellular matrix creation, and vascularization, to mention a few, are all part of the essential multidimensional information. Ultrasound imaging can be an excellent tool for both preclinical and clinical applications due to its inherent advantages of non-invasiveness and non-destructiveness.
Title : Graphene, butterfly structures, and stem cells: A revolution in surgical implants
Alexander Seifalian, University of London, United Kingdom
Title : Eliminating implants infections with nanomedicine: Human results
Thomas J Webster, Interstellar Therapeutics, United States
Title : Precision in cartilage repair: Breakthroughs in biofabrication process optimization
Pedro Morouco, Polytechnic of Leiria, Portugal
Title : Biodistribution and gene targeting in regenerative medicine
Nagy Habib, Imperial College London, United Kingdom
Title : Innovative educational strategies in tissue engineering: Integrating research into higher education
Laurie Mans, University of Applied Biosciences Leiden, Netherlands
Title : Keratin-TMAO wound dressing promote tissue recovery in diabetic rats via activation of M2 macrophages
Marek Konop, Medical University of Warsaw, Poland