Tissue engineering has emerged as a promising approach with two main goals: (1) developing tissue and organ substitutes for clinical transplantation to replace damaged regions and restore organ function, and (2) developing human tissue chips to replace animal models for drug screening and disease modelling. Till date, existing methods have been used to accurately arrange cells at dimensions ranging from single cells to complete tissue architectures, achieving several levels of complexity. Simple flat tissue transplants, such as skin and bladder, have shown clinical success because they include few cell types and require simpler engineering designs. In order to repair or replace lost tissues due to injury, disease, or age, strategies to generate functional organs and tissues are of significant interest for use in regenerative medicine. The Food and Drug Administration (FDA) has approved and made available several new therapy alternatives, including stem cell treatments and tissue-engineered substitutes for specific conditions. To support the individual organ function, each organ has its own distinct structural components, such as diverse cell types, matrix, and architecture, as well as a biophysical environment—pressure and flow—and biochemical stimuli—oxygen tension, cytokines, and growth factors.
Title : A revolution or surrender: The success and failures of tissue engineering and regenerative medicine
Thomas J Webster, Hebei University of Technology, United States
Title : Efficacy and safety outcomes in patients with chronic traumatic brain injury: Final analysis of the randomized, double-blind, surgical sham-controlled phase 2 STEMTRA trial
Bijan Nejadnik, SanBio, Inc, United States
Title : Light-based bioprinting: From bioink design to modulation of cell response in bioprinted hydrogels
Ruben F Pereira, University of Porto, Portugal
Title : Biofabrication of functional human intestinal tissue with villi and crypts using high-resolution 3D printing technique
Lindy Jang, Lawrence Livermore National Laboratory, United States
Title : Embracing the potential of biopolymer based hydrogel: The new frontier in chronic wound therapy
Madhu Gupta, School of Pharmaceutical Sciences, India
Title : A 3D -bioprinted in vitro adipose tissue model for the study of macrophage polarisation and function within metabolic disease.
Tiah Oates, University of Bristol, United Kingdom