Organoids are three-dimensional miniature organs grown in vitro from stem cells, replicating the structural and functional complexity of actual tissues. These tiny, self-organizing structures have gained prominence in biomedical research due to their potential to mimic the intricacies of human organs, offering a more accurate representation than traditional cell cultures. Organoids have been developed for various organs, including the brain, liver, kidney, and intestine, enabling researchers to study organ development, disease mechanisms, and drug responses. Their ability to recapitulate organ-specific functions makes them invaluable for personalized medicine and drug testing, as well as for understanding diseases like cancer. Organoids have also been utilized in regenerative medicine, holding promise for tissue repair and transplantation. Their applications extend to the study of infectious diseases, providing a platform for investigating host-pathogen interactions. Despite their tremendous potential, challenges such as standardization, scalability, and vascularization remain, and ongoing research aims to address these issues to unlock the full potential of organoids in advancing medical knowledge and therapeutic development.
Title : AI-integrated high-throughput tissue-chip for space-based biomanufacturing applications
Kunal Mitra, Florida Tech, United States
Title : Will be updated soon...
Vasiliki E Kalodimou, European University-Cyprus Ltd, Cyprus
Title : Will be updated soon...
Nagy Habib, Imperial College London, United Kingdom
Title : Will be updated soon...
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, United Kingdom
Title : Advanced 3D tissue models: Pioneering tools for investigating health and disease
Lucie Bacakova, Institute of Physiology of the Czech Academy of Sciences, Czech Republic
Title : Developing iPSC-derived 3D Outer Blood-Retinal Barrier Disease Models of Choroideremia for Gene Therapy Evaluation
Aradhana Kasimsetty, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), United States