Organoids are three-dimensional miniature organs grown in vitro from stem cells, replicating the structural and functional complexity of actual tissues. These tiny, self-organizing structures have gained prominence in biomedical research due to their potential to mimic the intricacies of human organs, offering a more accurate representation than traditional cell cultures. Organoids have been developed for various organs, including the brain, liver, kidney, and intestine, enabling researchers to study organ development, disease mechanisms, and drug responses. Their ability to recapitulate organ-specific functions makes them invaluable for personalized medicine and drug testing, as well as for understanding diseases like cancer. Organoids have also been utilized in regenerative medicine, holding promise for tissue repair and transplantation. Their applications extend to the study of infectious diseases, providing a platform for investigating host-pathogen interactions. Despite their tremendous potential, challenges such as standardization, scalability, and vascularization remain, and ongoing research aims to address these issues to unlock the full potential of organoids in advancing medical knowledge and therapeutic development.
Title : Eliminating implants infections with nanomedicine: Human results
Thomas J Webster, Interstellar Therapeutics, United States
Title : Graphene, butterfly structures, and stem cells: A revolution in surgical implants
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, London NW1 0NH, United Kingdom
Title : Biodistribution and gene targeting in regenerative medicine
Nagy Habib, Imperial College London, United Kingdom
Title : Precision in cartilage repair: Breakthroughs in biofabrication process optimization
Pedro Morouco, Polytechnic of Leiria, Portugal
Title : AI-integrated high-throughput tissue-chip for brain aging
Kunal Mitra, Florida Tech, United States
Title : Assembly and stability of on-chip microvasculature
Kara E McCloskey, University of California, Merced, United States