Preclinical animal testing is used to give reasonable data prior to early feasibility testing in people and human clinical trials in order to show that new technologies and therapies are safe and effective. During the nonclinical phase, animal models can help support and develop medical product development. Animal models that are well-designed can solve regulatory safety issues and provide further de-risking during product validation. Animal models can be used to evaluate minimum viable products and prototypes, which can help with quality assurance and compliance. To avoid superfluous preclinical research, a roadmap for product innovation strategies (regulatory, reimbursement) must be developed. Preclinical animal model safety and efficacy data are an important aspect of medical device development and are required to make these judgments. Before moving on to costly human trials, this can assist evaluate if the gadget is effectively tackling an actual need. Academic centers, which are generally based in linked veterinary medicine schools, provide unique resources that might help academic entrepreneurs fill this preclinical need.
Title : Graphene, butterfly structures, and stem cells: A revolution in surgical implants
Alexander Seifalian, University of London, United Kingdom
Title : Eliminating implants infections with nanomedicine: Human results
Thomas J Webster, Interstellar Therapeutics, United States
Title : Precision in cartilage repair: Breakthroughs in biofabrication process optimization
Pedro Morouco, Polytechnic of Leiria, Portugal
Title : Biodistribution and gene targeting in regenerative medicine
Nagy Habib, Imperial College London, United Kingdom
Title : Innovative educational strategies in tissue engineering: Integrating research into higher education
Laurie Mans, University of Applied Biosciences Leiden, Netherlands
Title : Keratin-TMAO wound dressing promote tissue recovery in diabetic rats via activation of M2 macrophages
Marek Konop, Medical University of Warsaw, Poland