Red Blood Cells (RBCs), also known as erythrocytes, are vital components of the circulatory system responsible for transporting oxygen from the lungs to tissues and organs throughout the body. Characterized by their biconcave disc shape, RBCs possess a flexible membrane that allows them to squeeze through narrow capillaries and efficiently navigate the bloodstream. These cells lack a nucleus and most organelles, maximizing their oxygen-carrying capacity. The red color of RBCs is attributed to hemoglobin, a protein that binds with oxygen in the lungs and releases it in tissues. The lifespan of a red blood cell is approximately 120 days, after which they are removed by the spleen and liver. Erythropoietin, a hormone produced by the kidneys, regulates the production of red blood cells in response to oxygen levels. Anemia, a condition characterized by a reduced number of RBCs or insufficient hemoglobin, can lead to fatigue and diminished oxygen transport. Understanding the physiology of red blood cells is crucial for diagnosing and managing various blood disorders and contributes to advancements in transfusion medicine and therapies related to oxygen transport in the human body.
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