Retina Horizontal Cells are specialized neurons found in the outer molecular layer of the retina, contributing to the intricate neural circuitry involved in visual processing. These cells play a crucial role in modulating signals within the retina by forming lateral connections between photoreceptor cells and bipolar cells. Divided into two main types, A and B, horizontal cells mediate inhibitory interactions that enhance the contrast and spatial resolution of visual information. A-type horizontal cells connect to cones, the photoreceptor cells responsible for daylight vision, while B-type horizontal cells connect to both rods and cones. The inhibitory influence of horizontal cells prevents the spread of signals laterally across the retina, facilitating the detection of finer details and edges in visual stimuli. Dysfunction in horizontal cell signaling may contribute to visual impairments, including changes in contrast sensitivity. The intricate network formed by horizontal cells is crucial for refining visual information before it is transmitted to higher visual centers in the brain. Ongoing research in retinal horizontal cells provides valuable insights into the complexities of visual processing and holds potential implications for understanding and treating various retinal disorders.
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