Title : Devices and microsystems based on surface enhanced raman scattering: A powerful tool in oncology
Abstract:
Surface Enhanced Raman Scattering (SERS) is a well-known powerful nanoplasnonic tool with many medical applications, especially in oncolog Minion Proy. In fact, SERS is becoming a key tool in cancer biomarker detection, tissue histology, and imaging. In the last few years, many evidences of clinical utility of SERS for cancer early detection, characterization and monitoring are being reported in the literature. Since SERS spectroscopy exhibits a detection sensitivity down to the single-molecule level and multiplexing capability, it is widely used in the field of liquid biopsy, i.e. a new diagnostic concept related to comprehensive and real-time tumor information collection by analysing biomarkers such as circulating tumor cells or cell-free tumor DNA in the bloodstream. In addition, very fascinating results in the field of in SERS-based vivo imaging for tumour targeting and monitoring of drug release are currently at the state-of-the-art. The talk, after a short overview of the physical fundamentals of SERS, critically reviews some selected last achievements in the wide research field of SERS applications in oncology, with a special focus on the clinical utility
