When cells proliferate out of control, cancer develops. Cancerous cells can arise in almost any portion of the body and spread to other parts. Multiple myeloma is a plasma cell malignancy. The immune system relies on normal plasma cells, which are present in the bone marrow. The immune system is made up of various cell types that collaborate to fight infections and other disorders. T cells and B cells are examples of lymphocytes (lymph cells), which are one of the main types of white blood cells in the immune system. Lymphocytes can be found in a variety of places throughout the body, including lymph nodes, bone marrow, the intestines, and the circulation.
Bone marrow can be discovered in the middle of certain bones. Blood-forming cells, fat cells, and supportive tissues make up this organ. Blood stem cells make up a modest percentage of the blood-forming cells. To create new blood cells, stem cells are required. Myelodysplastic syndromes are a group of rare diseases in which your body stops producing enough healthy blood cells. Myelodysplastic syndromes (MDS) are diseases that develop when the bone marrow's blood-forming cells become aberrant. Low numbers of one or more types of blood cells are the result of this.
Title : Myeloid neoplasms and molecular genetic alterations (Germline vs Somatic) that characterize specific entities in pediatric patients
Aida I Richardson, Ann & Robert H. Lurie Children's Hospital of Chicago, United States
Title : Overview of 2021 guidelines on the diagnosis of Von Willebrand Disease (VWD)
Maryam Asif, University of Washington, United States
Title : Clonal evolution in children with inherited bone marrow failure syndromes
Raykina Elena, Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Russian Federation
Title : Defining the clinical contribution of platelet-derived FXIII-A to regulation of fibrinolysis
Fahad S Alshehri, King Faisal Medical City for Southern Region, Saudi Arabia
Title : Prevalence of thalassemia and hemoglobinopathy in eastern India A 10-year high-performance liquid chromatography study of 119,336 cases
Santosh Kumar Mondal, Department of Pathology and Laboratory Medicine AIIMS, India
Title : Age-dependent trends in the expression of major haemoglobin types among infants of African descent in the first twenty-four months of life
Zaccheaus Awortu Jeremiah, Rivers State University, Nigeria