Skin Cells, collectively forming the epidermis, are the outermost layer of the body's integumentary system, serving as a protective barrier against environmental factors, pathogens, and dehydration. The primary types of skin cells include keratinocytes, melanocytes, Langerhans cells, and Merkel cells. Keratinocytes are the predominant cells in the epidermis, responsible for producing the protein keratin, which provides structural strength and waterproofing to the skin. Melanocytes produce melanin, the pigment responsible for skin color and UV protection. Langerhans cells are immune cells that contribute to the skin's defense against pathogens, while Merkel cells function as touch receptors. The epidermis continually undergoes cell turnover through a process known as desquamation, where old cells are shed and replaced by new ones from the basal layer. This renewal helps maintain the skin's integrity and appearance. Skin cells communicate through complex signaling pathways, responding to environmental cues and regulating processes like inflammation and wound healing. UV radiation, for example, triggers melanocytes to produce more melanin, protecting the skin from sun damage. Disorders affecting skin cells range from common conditions like acne and eczema to more serious issues such as skin cancer. Skin cell regeneration is influenced by factors like age, genetics, and overall health, with younger individuals generally experiencing faster turnover.
Title : AI-integrated high-throughput tissue-chip for space-based biomanufacturing applications
Kunal Mitra, Florida Tech, United States
Title : Will be updated soon...
Vasiliki E Kalodimou, European University-Cyprus Ltd, Cyprus
Title : Will be updated soon...
Nagy Habib, Imperial College London, United Kingdom
Title : Will be updated soon...
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, United Kingdom
Title : Advanced 3D tissue models: Pioneering tools for investigating health and disease
Lucie Bacakova, Institute of Physiology of the Czech Academy of Sciences, Czech Republic
Title : Developing iPSC-derived 3D Outer Blood-Retinal Barrier Disease Models of Choroideremia for Gene Therapy Evaluation
Aradhana Kasimsetty, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), United States