Alexander Seifalian, BioScience Innovation Centre, United Kingdom
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2nd Edition of International Conference on Tissue Engineering and Regenerative Medicine
September 16-17, 2022 (Online Event)
TERM C 2022
Keynote Presentation
Oral Presentation
Victor A, Indian Institute of Science, India
Snail mucin, obtained from snails, is a complex substance that has been recounted to contain glycosaminoglycans (GaGs), allantoin, hyaluronic acid, elastin, and glycolic acid. Some of these constituents, especially GaGs, are essential for reducing cartilage deterioration and infl [....] » Read More
Oral Presentation
Pratikshkumar Rameshbhai Patel, CSIR-National Chemical Laboratory, India
Curcumin (Cur) is a natural polyphenol with multifaceted pharmacological functions, exploited extensively for biomedical applications. Traditionally curcumin is being used as an antimicrobial agent. However, to improvise the pharmacological properties, it is being modified synthe [....] » Read More
Oral Presentation
Neha Ashok Waghmare, Pandorum Technologies Pvt. Ltd, India
Cornea is the first transmitting layer of the eye, responsible for 75% of its refractive power. Damage to the cornea can cause blindness, which affects over 12 million people worldwide. While corneal transplant remains the sole treatment option to restore vision in many severe ca [....] » Read More
Oral Presentation
Madhu Gupta, Research University, India
Placental extract formulation Regenerin (Patent no- RU 2469704 CI, dt: 07.07.2011) has been reported to possess antioxidant, antimicrobial, anti-inflammatory, cellular proliferation, and tissue regeneration properties. Considering the properties of placental extract, the present [....] » Read More
Oral Presentation
Karma Pace, Harrisburg University, United States
L1CAM (L1, CD171) is a cell surface immunoglobulin superfamily protein normally involved in axon guidance, differentiation, and cell migration during development. LI also is expressed abnormally in many types of cancers including breast, pancreatic, colon, melanoma and glioma, an [....] » Read More
Oral Presentation
Sara Ibrahim AlSalhi, University of Liverpool, United Kingdom
MMP13 is a primary catabolic factor involved in cartilage degradation through its ability to cleave type II collagen. Transcriptionally, MMP13 is regulated by 2 main elements; proximal promoter and distal enhancers. The aim of the study is to identify transcriptional elements tha [....] » Read More
Oral Presentation
Brunel Arthur, University of Limoges, France
Hydroxyapatite (HA) is a highly biocompatible calcium phosphate ceramic but lacks stimulatory properties to sustain large bone graft substitutes. Successful osseointegration of large HA scaffolds requires vascularization within the porous network through angiogenesis stimulation. [....] » Read More
Oral Presentation
Ika Ayu, Udayana University, Indonesia
Background: Based on the Anti Aging Medicine concept, the aging process can be delayed, prevented, treated and returned to condition such as young age in a healthy state. In the end,life expectancy becomes longer and stays healthy. Dyslipidemic is an abnormalities in lipid metabo [....] » Read More
Oral Presentation
Rodrigo Osorio, UNAM, Mexico
Polylactic acid (PLA) has been broadly used for many applications, due to its novel properties such as good biodegradable material and thermoplastic stability. In consequence, it is consider a highly adequate candidate for medical and biological applications. Diverse methods have [....] » Read More
Oral Presentation
Vyacheslav Shulunov, Institute of Physical Materials Science, Siberian Branch of the Russian Academy of Sciences, Russian Federation
Developed a Rapid Parallel Search (RPS) technology shows keys to preventing the spread of virus outbreaks by exactly and quickly identify sick and asymptomatic carriers. RPS uses the time-tested Scanning Electron Microscopy (SEM) and Artificial Neural Network (ANN) methods for de [....] » Read More
Poster Presentation
Silindile Ngcobo, University of Cape Town, South Africa
Fibrinogen is an attractive candidate for a wide range of regenerative treatments due to its bioactivity and FDA-approval. Aim: We therefore sought to modify fibrinogen through covalent attachment of heparin. Heparin is desirable as it binds a significant number of growth fact [....] » Read More
Poster Presentation
Alessandro Bertolo , Swiss Paraplegic Research, Switzerland
Pressure injuries (PI) are chronic wounds caused by increased pressure over a prolonged period of time. Interruption of blood circulation leads to a shortage of oxygen, nutrient supplies, accumulation of toxic by-products and tissue necrosis. Patients with spinal cord injury (SCI [....] » Read More
Poster Presentation
Sara Darakhshan, Kermanshah University of Medical Sciences, Iran (Islamic Republic of)
Uncontrolled bleeding is the primary reason for death in traumatic conditions and surgeries. Excessive bleeding causes a loss of hemodynamics, which leads to the need to receive blood, prolongs surgery time, and imposes significant costs on the health system. Therefore, using saf [....] » Read More
Poster Presentation
Yusser Olguin, Federico Santa Maria Technical University, Chile
Electrical stimulation in nerve tissue engineering is a way to promote cell differentiation, which experimentally demonstrates efficiency and characteristics dependent on the form of stimulation. Considering that the materials used to develop scaffolds usually incorporate chemica [....] » Read More
Poster Presentation
Congdi Xu, Tongji University, China
The heterogeneity of GBM leads to tumor recurrence and treatment resistance, and the complex tumor microenvironment hinders organoid progression. Considering the important role of hyaluronic acid in GBM progression, here we introduce a novel approach to mimic ECM composition by m [....] » Read More
Poster Presentation
Mahdieh Ghiasi, Tehran University of Medical Sciences, Iran (Islamic Republic of)
Background: Platelet-rich fibrin (PRF) is one of bone therapies in craniofacial surgery and dentistry. PRF contains many bioactive molecules such as growth factor beta-1 (TGF-β1), platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), epidermal gro [....] » Read More
Title : Electroactive polymer-based smart scaffolds for tissue engineering and regenerative medicine
Federico Carpi, University of Florence, Italy
Cellular scaffolds are a critical component of any system for tissue engineering and regenerative medicine. So far, poor attention has been focused on scaffolds that can mimic the extracellular matrix not only statically, but also dynamically, especially for tissues that have to [....] » Read More
Title : Mechanical modulation of cell response in 3D bioprinted hydrogels
Ruben F Pereira, University of Porto, Portugal
The fabrication of human tissues and organs exhibiting structural, mechanical and biological function remains a major challenge due to their structural complexity, multicellular composition, spatial heterogeneity of the ECM and, in most cases, the presence of a vascular network. [....] » Read More
Title : Xenografts and genomic in cancer research from invertebrates to vertebrates with the sea star as a model of study
Michel Leclerc, Orleans University, France
We performed ,in 1975, the first heterotransplantation of invertebrate A.O in nude mouse, then a double heterotransplantation of human tumor and Axial organ next to this last one, always in nude mouse: The human tumor was rejected in 50% of observed cases.Some years later,&nbs [....] » Read More
Title : Curvotaxis mechanism in single cells and epithelia
Laurent Pieuchot, Universite de Haute-Alsace, France
Cells can migrate individually between tissues and organs or collectively in tightly or loosely associated groups. In both cases, cell migration is regulated by extracellular cues of very different natures. Here I will describe a cellular mechanism called curvotaxis that enables& [....] » Read More
Title : Open abdomen and negative pressure wound therapy for acute peritonitis especially in the presence of anastomoses and ostomies
Orestis Ioannidis, Aristotle University of Thessaloniki, Greece
Acute peritonitis is a relatively common intra-abdominal infection that a general surgeon will have to manage many times in his surgical carrier. Usually it is a secondary peritonitis caused either by direct peritoneal invasion from an inflamed infected viscera or by gastrointest [....] » Read More
Title : Pathogenic Alpha-synuclein cell-to-cell transmission mechanism and related therapeutic development
Xiaobo Mao, Johns Hopkins University School of Medicine, United States
α-Synucleinopathies is characterized with accumulation of misfolded α-synuclein (α-syn), including Parkinson’s disease (PD), Dementia with Lewy Bodies (DLB), and Multiple System Atrophy (MSA). Emerging evidence indicates that pathogenesis of α-synucl [....] » Read More
Title : High-throughput in vitro analysis of engineered tumour microenvironments using 3D bioprinting
Panthipa Suwannakot , UNSW Sydney, Australia
Traditional 2D flat cell cultures of cancer cells and in vivo animal experiments remain the most commonly used techniques as in vitro and in vivo platforms for cancer research, drug screening and toxicity tests prior to entering human clinical trials. This is due to their low cos [....] » Read More
Title : Is 3D bioprinting innovation falling down at the patentability hurdle?
Pratap Devarapalli, University of Tasmania, Australia
Patent applications around the world must go through a stringent examination procedure before they can be granted. During the examination procedure, patent examiners assess a patent application in light of patentability criteria such as patentable subject matter, novelty, inventi [....] » Read More
Title : Design of 3D bioengineered personalized scaffolds to potentiate bone ingrowth and angiogenic network for oral tissues reconstruction
Christiane Salgado , Institute of Research and Innovation in Health(i3S), Brazil
Population ageing (>70 years) and associated risk factors (alcohol addiction and smoke - 85%) increase the number of oral cancer (more frequently, head and neck squamous cell carcinoma - HNSCC) cases requiring large bone defects repair, raising the need for bone and oral mucos [....] » Read More
Title : Altering stem cell states by controlling cell signaling information
Mohan Malleshaiah, Montreal Clinical Research Institute, Canada
Cell fate determination induced by cell signaling is central to stem cells and regenerative medicine. Pluripotent stem cells such as embryonic stem cells (ESC) are an attractive model for understanding the relationship between cell signaling and cell fates. Cultured mouse ESCs ar [....] » Read More
Title : Mechanobiology in neural tissue regeneration
Anthi Ranella, Institute of Electronic Structure and Laser (IESL), Greece
The peripheral nervous system consists of glial cells and neurons that receive the necessary chemical, physical, and mechanical stimuli for their adhesion, proliferation, and differentiation from their extracellular milieu. Mechanotransduction refers to the ability of a cell to [....] » Read More
Title : Fabricating humans: Ethical, legal and social Issues of 3D organ bioprinting
Elena Salvaterra, Department of Education, Italy
Biofabrication and bioprinting represent an emerging new science promising astonishing progresses in the research and clinical applications. Biofabrication and bioprinting are “cousins” of tissue engineering and regenerative medicines because they use human biological [....] » Read More
Title : RADA16-I based scaffolds for wound healing and regenerative medicine
Deptula Milena, Medical University of Gdansk, Poland
In regenerative medicine there is a strong need for therapeutic delivery systems and tissue scaffolds. Additionally, wound healing complications affect thousands of people each year. The biggest problem constitute chronic wounds, e.g. diabetic ulcers. Currently available methods [....] » Read More
Title : Recellularized organs as ex vivo models for colorectal cancer metastasis
Onwuegbuchulam Olachi Angelica, University Hospital Muenster Germany, Germany
Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide. The main factor leading to mortality is the development of metastasis, mostly occurring in the liver. Reasons why the liver is the main metastatic site for CRC and which factors lead to inv [....] » Read More