New cancer markers have been discovered in the form of male and female oncogene peptide protein and its anti-peptide antibodies. They were found in both salvia and blood samples of females with breast cancer and a male with prostate cancer, in a pilot study for fifteen married pa [....] » Read More
Purpose This study aimed to improve the management of ovarian metastases (OM) in colorectal cancer (CRC) by evaluating the clinicopathological characteristics, therapeutic strategies, and prognostic factors associated with OM originating from CRC. Methods Medical records of pa [....] » Read More
Three industrial waste incinerators (IWIs) were built in 1999, 2001, and 2010, within a 3 km radius of a town with a population of around 5000 in Korea. This study evaluated whether residents near these three IWIs had increased cancer incidence than those from other areas in Kore [....] » Read More
Background Fluoropyrimidine based-drugs, such as capecitabine and 5-fluorouracil, are used to treat a variety of cancers.1 Deficiency of dihydropyrimidine dehydrogenase (DPD), an enzyme that catabolises fluoropyrimidines, significantly increases risk of drug toxicity1, theref [....] » Read More
Breast Cancer is ranked as the number one cancer among Indian Females with very high incidence rates. The lack of knowledge among the women of urban India regarding risk factors and screening practices can cause delay in diagnosis. Estimating and improving awareness can contribut [....] » Read More
Sinonasal undifferentiated carcinoma is a rare malignancy, of the nasal cavity and/ or paranasal sinuses accounting to be less than 1% of all malignancies. This case report will discuss a young male patient diagnosed with poorly differentiated carcinoma in the lateral wall o [....] » Read More
Background: The combination of phytochemicals with chemotherapy drugs is an emerging new strategy forcancer therapy to increase antitumor responses. Methods: The present study investigates the effect of the combination of capsaicin (CAP) with cisplatin (DDP) and the potenti [....] » Read More
Keywords: QRN substance, Novel Substance, Non-small cell lung cancer, Novel Therapy Introduction:Cancer is a scary name even though it is named after an innocent animal, even called a disease. It has sought the door to many different ideas working to experience many other theo [....] » Read More
Background: Nasopharyngeal cancer (NPC) is one of the most common cancers in head and neck. Understanding the current epidemiological profile of international variations in NPC incidence and mortality and predicting the future NPC burden allows policymakers to make evidence-based [....] » Read More
Patients receiving treatment for cancer by any modality are likely to experience side effects that affect their ability or desire to consume a variety of nutritious foods. This is a critical issue as maintaining good nutrition and health during treatment may affect patient tolera [....] » Read More
This presentation will focus on the advancements made in cancer biomarkers. Cancer biomarkers can be important in identifying targeted treatment options and personalizing the cancer treatment based on the genomic profile of the tumor. Studies have been published that provide evid [....] » Read More
Patients who are undergoing pelvic radiation should be assessed for urinary tract infections, and based on this, those patients who are symptomatic like burning micturition or dysuria developed during radiation have to be evaluated based on urine culture and sensitivity reports a [....] » Read More
Targeted cancer therapy often causes fewer adverse effects than traditional chemotherapy drugs. Thus, targeted therapeutic drugs have become mainstream of several hematologic and solid malignancies including non-small cell lung cancer (NSCLC). The first anaplastic lymphoma kinase [....] » Read More
Title : Novel mechanisms of the abscission checkpoint in human cells
George Zachos, University of Crete, Greece
Chromatin bridges are strings of chromatin connecting the anaphase poles or daughter nuclei and have been linked to tumourigenesis. In response to chromatin bridges in cytokinesis, eukaryotic cells delay abscission, the severing of the narrow cytoplasmic canal that connects the t [....] » Read More
Title : Sensor technology for detection of biomarkers in gynecological medicine
Michael Thompson, University of Toronto, Canada
Detection of gynecological disorders of female reproductive organs, especially forms of cancer, typically involves screening of symptoms for the illnesses, followed by imaging with ultrasound or MRI. These techniques are time consuming and require trained professionals to perform [....] » Read More
Title : Severe SARS-CoV-2 & Cancer: Unlocking the immunology with promising therapeutic interventions
Yan Leyfman, Icahn School of Medicine, United States
Coronavirus disease 2019 (COVID-19), a respiratory illness caused by betacoronavirus SARS-CoV-2, has broad clinical presentations ranging from asymptomatic to fatal outcomes. Due to their immunocompromised status, cancer patients are at an increased risk for severe SARS-CoV-2 inf [....] » Read More
Title : Relation of luminal and myoepithelial cells in “nuclear-inverse polarity papillary lesions lacking myoepithelail cells” of the breast
Shinya Tajima, Shizuoka Medical Center, Japan
Breast papillary lesions exhibit broad range. Tajima et al. reported in discrimination between benign intraductal papilloma (IDP) and malignant endocrine ductal carcinoma in situ (E-DCIS), new marker of CD56 is useful for discriminating between benign and malignant. Relationship [....] » Read More
Title : Dietary patterns and nonalcoholic fatty liver disease: A systematic review of observational and interventional studies
Maryam Hashemian, Utica University, United States
Background & Aims: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease that may progress to hepatocellular carcinoma. Dietary intake strongly influences its development and should be a component of any prevention and treatment plan strategy. [....] » Read More
Title : Efficacy and toxicity for CD7 chimeric antigen receptor T- Cell therapy in patients with relapsed/refractory T- Cell lymphoma
Fan Yang, Beijing Gobroad Boren Hospital, China
Background: The prognosis of refractory/relapsed T-cell lymphoma is extremely poor, especially for the patients who failed to allogeneic hematopoietic stem cell transplantation(alloHSCT). Aims: The aim was to assess humanize CD7 chimeric antigen receptor (CAR) T-cell safety an [....] » Read More
Title : Co- Targeting of specific epigenetic regulators in combination with CDC7 potently inhibit melanoma growth
Romi Gupta, University of Alabama, United States
Melanoma is a highly aggressive skin cancer that frequently metastasizes, but current therapies only benefit some patients. Here, we demonstrate that the serine/threonine kinase cell division cycle 7 (CDC7) is overexpressed in melanoma, and patients with higher expression have sh [....] » Read More
Title : Differentially expressed genes between wild type and drug resistant human cervical cancer cell lines
Nauf Bou Antoun, Kingston University, United Kingdom
Background: Cervical cancer although is highly preventable, is still the 4th most common cancer in women globally. World Health Organization estimate 640,000 new cases and 342,000 deaths in 2020, indicating the need for effective treatment at late stages of the disease, when it i [....] » Read More
Title : Explainable gastric cancer risk prediction: machine learning based models trained on data from regular health check-up programs of asymptomatic screening population
Ji Hyun Song, Seoul National University Hospital Healthcare System Gangnam Center, Korea, Republic of
Backgroud: Since early diagnosis and treatment of gastric cancer increases the survival rate, regular gastric cancer screening is recommended for the high-risk group of gastric cancer. Objective risk stratification and assessment would be helpful to develop personalized stra [....] » Read More