Sherif Salah, Private Research Center, Egypt
New cancer markers have been discovered in the form of male and female oncogene peptide protein and its anti-peptide antibodies. They were found in both salvia and blood samples of females with breast cancer and a male with prostate cancer, in a pilot study for fifteen married pa [....] » Read More
Title : Novel mechanisms of the abscission checkpoint in human cells
George Zachos, University of Crete, Greece
Chromatin bridges are strings of chromatin connecting the anaphase poles or daughter nuclei and have been linked to tumourigenesis. In response to chromatin bridges in cytokinesis, eukaryotic cells delay abscission, the severing of the narrow cytoplasmic canal that connects the t [....] » Read More
Title : Sensor technology for detection of biomarkers in gynecological medicine
Michael Thompson, University of Toronto, Canada
Detection of gynecological disorders of female reproductive organs, especially forms of cancer, typically involves screening of symptoms for the illnesses, followed by imaging with ultrasound or MRI. These techniques are time consuming and require trained professionals to perform [....] » Read More
Title : Severe SARS-CoV-2 & Cancer: Unlocking the immunology with promising therapeutic interventions
Yan Leyfman, Icahn School of Medicine, United States
Coronavirus disease 2019 (COVID-19), a respiratory illness caused by betacoronavirus SARS-CoV-2, has broad clinical presentations ranging from asymptomatic to fatal outcomes. Due to their immunocompromised status, cancer patients are at an increased risk for severe SARS-CoV-2 inf [....] » Read More
Title : Relation of luminal and myoepithelial cells in “nuclear-inverse polarity papillary lesions lacking myoepithelail cells” of the breast
Shinya Tajima, Shizuoka Medical Center, Japan
Breast papillary lesions exhibit broad range. Tajima et al. reported in discrimination between benign intraductal papilloma (IDP) and malignant endocrine ductal carcinoma in situ (E-DCIS), new marker of CD56 is useful for discriminating between benign and malignant. Relationship [....] » Read More
Title : Dietary patterns and nonalcoholic fatty liver disease: A systematic review of observational and interventional studies
Maryam Hashemian, Utica University, United States
Background & Aims: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease that may progress to hepatocellular carcinoma. Dietary intake strongly influences its development and should be a component of any prevention and treatment plan strategy.  [....] » Read More
Title : Efficacy and toxicity for CD7 chimeric antigen receptor T- Cell therapy in patients with relapsed/refractory T- Cell lymphoma
Fan Yang, Beijing Gobroad Boren Hospital, China
Background: The prognosis of refractory/relapsed T-cell lymphoma is extremely poor, especially for the patients who failed to allogeneic hematopoietic stem cell transplantation(alloHSCT). Aims: The aim was to assess humanize CD7 chimeric antigen receptor (CAR) T-cell safety an [....] » Read More
Title : Co- Targeting of specific epigenetic regulators in combination with CDC7 potently inhibit melanoma growth
Romi Gupta, University of Alabama, United States
Melanoma is a highly aggressive skin cancer that frequently metastasizes, but current therapies only benefit some patients. Here, we demonstrate that the serine/threonine kinase cell division cycle 7 (CDC7) is overexpressed in melanoma, and patients with higher expression have sh [....] » Read More
Title : Differentially expressed genes between wild type and drug resistant human cervical cancer cell lines
Nauf Bou Antoun, Kingston University, United Kingdom
Background: Cervical cancer although is highly preventable, is still the 4th most common cancer in women globally. World Health Organization estimate 640,000 new cases and 342,000 deaths in 2020, indicating the need for effective treatment at late stages of the disease, when it i [....] » Read More
Title : Explainable gastric cancer risk prediction: machine learning based models trained on data from regular health check-up programs of asymptomatic screening population
Ji Hyun Song, Seoul National University Hospital Healthcare System Gangnam Center, Korea, Republic of
Backgroud: Since early diagnosis and treatment of gastric cancer increases the survival rate, regular gastric cancer screening is recommended for the high-risk group of gastric cancer. Objective risk stratification and assessment would be helpful to develop personalized stra [....] » Read More