Among currently available HIV-1 inhibitors hamper the polymerase activity of HIV-1 through allosterically binding to the binding pocket but geometry of the DNA and its cycle emergence mutations (especially K103N,Y181C) rapidly develop resistance and potency, efficacy is an anothe [....]
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This research explores the synthesis, characterization, and biological evaluation of quinazoline derivatives using green chemistry principles for sustainable pharmaceutical development. By adopting environmentally responsible strategies—such as using renewable feedstocks, n [....]
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Shape memory alloys take place in a class of advanced smart materials by exhibiting a peculiar property called shape memory effect. This phenomenon is initiated with thermomechanical processes on cooling and deformation and performed thermally on heating and cooling, with which s [....]
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Title : Design space filling model, synthesis and evaluation of novel 2-indolinone HIV-1 inhibitors
Rahul Hajare, Sandip University, India
Among currently available HIV-1 inhibitors hamper the polymerase activity of HIV-1 through allosterically binding to the binding pocket but geometry of the DNA and its cycle emergence mutations (especially K103N,Y181C) rapidly develop resistance and potency, efficacy is an anothe [....] » Read More
Title : Quinazolines: Green synthesis, characterization and biological activities
Jenifer Robinson, Indian School Alwadi AL Kabir, Oman
This research explores the synthesis, characterization, and biological evaluation of quinazoline derivatives using green chemistry principles for sustainable pharmaceutical development. By adopting environmentally responsible strategies—such as using renewable feedstocks, n [....] » Read More
Title : Energy relations of thermomechanical processes and crystallographic transformations in shape memory alloys
Osman Adiguzel, Firat University, Turkey
Shape memory alloys take place in a class of advanced smart materials by exhibiting a peculiar property called shape memory effect. This phenomenon is initiated with thermomechanical processes on cooling and deformation and performed thermally on heating and cooling, with which s [....] » Read More