Abstract:
Introduction:
Optimal nutrition for the best immunological outcomes would be nutrition, which supports the functions of immune cells allowing them to initiate effective responses against pathogens and to resolve the response rapidly when necessary. Mulmina® Mango was developed for nutritional modulation of immune system. Nutritional modulation of the immune system has applications within the clinical setting, but can also have a role in healthy populations, acting to reduce or delay the onset of immune-mediated chronic diseases.
Material and Methods:
In this retrospective study we have evaluated role of Mulmina® Mango, Mango Juice based health drink with bioactive of Mango, Centella asiatica, turmeric along with various vitamins and minerals in improving health condition in viral infection (COVID-19), bacterial infection (RTI in children) and immune boosting property post vaccination (COVID-19). Mulmina® mango was developed to improve antioxidant capacity and immunity of induvial compromised due to different etiologies. Total four clinical trials (CT), BMCRI CT (120 subject), SPARSH CT (50 Subject), Post vaccination CT (300 Subjects), RTI CT (125 subjects) conducted in different institutions of India, were reviewed. These trials were approved by institutional ethical committee of respective institution and registered with CTRI.
Result:
As per the trial it was observed that Mulmina® Mango supplementation has a potential role in controlling the dysregulated immune system by reducing interferon gamma, increasing the immune shaping cells (CD4, CD8, IgA, IgG) to impart immune boosting effect. Mulmina® Mango helps in achieving higher antibody titer early and maintaining high titer for longer duration of time. Mulmina® Mango in Viral infection (COVID-19) along with Standard of care, has shown significant decrease in level of CRP and MDA than the control group. This indicated Mulmina® Mango supplementation can help in reduction of inflammation during infection cases.
These clinical trial shows, if standard of care is supplemented with Mulmina® Mango, it will increase SOD, CAT, and GSH in patient suffering form bacterial infection, Viral infection or during post vaccination. Dopamine level was found to be high after Mulmina® mango supplementation which helps in faster recovery and improve QoL in patient suffering from Viral and bacterial infection. There was no adverse effect was reported any of the study. This help us to conclude Mulmina® Mango was found to be safe and effective with the standard of care during these trials.
Conclusion:
Looking at the above result we can conclude Mulmina® Mango will be an effective supplement for increasing Immunity & antioxidant capacity in different type of viral, bacterial infection and also in post vaccination case. Its safety data indicates its safe in age group of subjects.
