Nutrition 2022

Sena Ardicli

Sena Ardicli, Speaker at Nutrition Conference 2022
Bursa Uludag University, Turkey
Title : Are we really what we eat? Molecular genetic aspects

Abstract:

Recently, it is very well known that good nutrition is essential for a healthy life. In this context, new nutritional supplements and extracts from different sources are introduced to the market. Scientific studies supported by in vitro and in vivo experimental designs are carried out on these products. But one important question is whether molecular genetic dynamics are altered by nutritional properties or vice versa. Understanding the relationship between nutrition and genetics can be achieved through two basic interactions. On one hand, nutrients may affect DNA stability and repair, important biological processes, such as apoptosis, and the expression levels of many genes. On the other hand, individual genotypes may alter metabolic pathways and the bioactivity of regulatory molecules through genetic variation components, such as single nucleotide polymorphisms and mutations. Genotype differences can also directly change the reflection of the effects of nutrients and metabolic mediators on the phenotype. Newly-identified epigenetic modifications and non-coding RNAs have made these interactions even more complicated. Controversial results in studies with nutritional supplements also draw attention. One of the main reasons for these results is that many extracts or supplements have multiple ingredients and it is difficult to determine from which molecule the effect observed in the experiments originates. Moreover, molecular changes in nutrients due to reactions in the digestive system make it difficult to verify in vitro results in in vivo models. This presentation focuses on how genotypic background influences nutritional traits, as well as how nutrition can alter genetic dynamics. In this context, current research results on the relationship between nutrition and genetics, the effects of relevant genetic markers, evaluation of nutrigenomic data, limitations in experimental designs, and controversial results will be discussed from molecular genetics and evolutionary perspectives.

Audience Take Away Notes:

  • Can nutrition affect genetic properties?
  • New insights into the role of feed supplements regarding molecular aspects.
  • Evaluations of different diet properties from the epigenetics perspective.
  • Recent findings from in vivo studies for feed additives that affect genetic properties.
  • The limitations of in vivo studies on the effects of feed supplements on genetic alterations.
  • The association of the genetic structure and nutritional dynamics.

Biography:

Dr. Sena Ardicli is an associate professor at the Bursa Uludag University, Faculty of Veterinary Medicine, Department of Genetics in Turkey. He received his first PhD degree in 2015 at the same institution. Dr. Ardicli started his second PhD at the Graduate School of Natural and Applied Sciences, Department of Biology in 2018. His areas of expertise are molecular biology and genetics, population genetics, genomic selection, meat science, and animal biotechnology. Dr. Ardıçlı has more than 120 publications related to his subject and has received many awards in different symposiums and congresses.

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