Abstract:
Introduction: Lymphatic system is the subject of lymphology and immunology research. The integration of sciences offers new approaches to solution the problem of ensuring endoecological safety of the organism and increasing non-specific resistance, especially in relation to senile age. Lymphonutriciology will provide new opportunities in increasing the protective function of the lymphatic system.
Methods: The experiment was carried out on 160 white rats of Wistar with conditionally isolated groups: «young» (age 3-5 months) and «old» (age 1.5-2 years). Half of the animals took the original phytocomposition from medicinal plants of Siberia in a daily dose of 0.1-0.2 g/kg for a month. Phytocomposition as a food supplement is important for nutrition and health. The subject of the study were lymph nodes of different localization. Histological, thermogravimetric, X-ray fluorescence analysis with synchrotron radiation, statistical methods were used.
Results: Aging is a negative process for the lymphatic system, leading to a decrease in drainage-detoxication and immune functions of lymph nodes in the lymphatic region. This is due to the change and destabilization of microelement exchange, hydration parameters and morphometric indicators of structural-functional zones lymph nodes. Ensuring lymph node operability is a condition of endoecological comfort in aging. This can be achieved using lymphotropic phytotechnology to building an original plant food additive. In this situation, the lymphatic system is a tool for providing drainage and detoxification of the endoecological space. Phytotherapy has a structural-modifying effect on the structure of the lymph node, restoring the size of compartments. We established a direct relationship between compartments and immune response intensity across humoral and cellular types. Medicinal plants are donors of trace elements and fill the deficiency of trace elements during aging. There is a direct relationship between trace elements and enzymes involved in lymphoid cell proliferation. The lymphoproliferative effect (neolymphogenesis) as a result of phytotherapy was first noted. There is the formation of temporary compensatory lymphoid structures – lymphoid follicles outside and inside the lymph node. The noted effects of phytotherapy correct the senile changes in lymphoid tissue when achieving the "dynamic age norm of health" in providing protection at the organ level (endoecology of the lymphatic region).
Conclusion: Lymphonutriciology is a new direction in nutrition to develop a lymphotropic food supplement. Food phytocomposition is the essence of lymphotropic phytotechnology. Lymphotropic phytotechnology is positioned as an opportunity to improve the quality of life and preserve health through the optimization of the structure and functions of the lymph node in the lymphatic region during aging.
