Title : Light-based bioprinting: From bioink design to modulation of cell response in bioprinted hydrogels
Ruben F Pereira, University of Porto, Portugal
The fabrication of human tissues and organs exhibiting structural, mechanical and biological function remains a major challenge due to their structural complexity, multicellular composition, spatial heterogeneity of the ECM and, in most cases, the presence of a vascular network. [....] » Read More
Title : A revolution or surrender: The success and failures of tissue engineering and regenerative medicine
Thomas J Webster, Hebei University of Technology, United States
In the 1990s, tissue engineering promised to change healthcare forever. Images on the cover of journals showed humans with almost every organ regenerated using tissue engineering approaches. From bone to skin to the brain to the heart, tissue engineering was destined to change th [....] » Read More
Title : Efficacy and safety outcomes in patients with chronic traumatic brain injury: Final analysis of the randomized, double-blind, surgical sham-controlled phase 2 STEMTRA trial
Bijan Nejadnik, SanBio, Inc, United States
BACKGROUND: Patients with traumatic brain injury (TBI) frequently experience chronic motor deficits, for which no approved pharmacological or biological agents are available. OBJECTIVE: To determine whether the stereotactic intracranial implantation of allogeneic modified bone [....] » Read More
Title : Biofabrication of functional human intestinal tissue with villi and crypts using high-resolution 3D printing technique
Lindy Jang, Lawrence Livermore National Laboratory, United States
The epithelium of the small intestine is composed of villi that protrude into the gut lumen like fingers and crypts that are epithelial invaginations. The architecture of villi and crypts is critical to maintain intestinal homeostasis and renewal. In recent years, researchers hav [....] » Read More
Title : A 3D -bioprinted in vitro adipose tissue model for the study of macrophage polarisation and function within metabolic disease.
Tiah Oates, University of Bristol, United Kingdom
Macrophages dynamically polarise into specialised phenotypes to perform an array of functions as part of both the innate immune response and tissue homeostasis. The ability of macrophages to polarise stems from the sensitivity of these cells to the local tissue environment. The c [....] » Read More
Title : Comparison of different nanofiber scaffolds effects on bone regeneration of calvaria defect in a wistar rat model _importance of porosity
Fanny Gimie, Gip Cyrio, France
Abstract Skeletal tissue injury is a major burden on the global healthcare system due to an aging population. In addition, metabolic disorders such as diabetes and osteoporosis further impede the healing process. Tissue engineering scaffold for reconstructive strategies offer exc [....] » Read More
Title : Influence of exposure to pesticides on telomere length and pregnancy outcome: Diethylphosphates but not dimethylphosphates are associated with accelerated telomere attrition in a Palestinian cohort
Jaber Jamil Haj Ali, University Medical Center, Germany
Exposure to environmental pesticides during pregnancy is associated with adverse health outcomes such as low birth weight and impaired neuro-development. In this study, we assessed maternal leukocyte telomere lengths (TL) in Palestinian pregnant women and compared the data with u [....] » Read More
Title : The development of an open-source low-cost 3d “micro”-bioprinter
Lauren R Harrison, McGill University, Canada
The impact of three dimensional (3D) bioprinting within the tissue engineering field has grown significantly in recent decades. 3D bioprinting allows for automated and accurate high- throughput fabrication of functional tissues and organs using a layer-by-layer bottom-up printing [....] » Read More
Title : Biodegradable ultrathin nanofibrous membranes for retinal tissue engineering
Hana Studenovska, Institute of Macromolecular Chemistry, Czech Republic
Degenerative retinal diseases such as age-related macular degeneration (AMD) impair the function of the retinal pigment epithelium (RPE), which results in failure of photoreceptors and loss of vision. Replacement of the RPE by a transplantation of retinal cells via nanofibrous me [....] » Read More
Title : Optimizing electrospun biodegradable small diameter vascular graft via 3D printing reinforcement achieved a long-term patency neotissue formation in a small animal model
Obiweluozor Francis Onyekachi, Chonnam University Hospital and Medical school, Korea, Republic of
Step-wise increase in cases of patients with cardiovascular disease globally has propelled scientist in this area to develop improved commercially available artificial blood vessel with large diameter for reducing adverse responds that drive acute thrombosis and the accompanying [....] » Read More
Title : Investigation of trace elements in Nigerian women with breast cancer using particle-induced xray emission (PIXE) analysis
Olaiya David Olubunmi, Obafemi Awolowo University, Nigeria
This study determined the variations in trace elements level in cancer patients, non-cancer patients and compared concentrations of trace elements in cancerous and non-cancerous breast tissues. This was with a few to understanding the effects of trace elements in the etiology of [....] » Read More
Title : Early and automatic breast cancer detection and screening using thermal imaging
Alamirew Kefale, University of Gondar, Ethiopia
Breast cancer is one of the deadliest forms of cancer in women but the disease has a good prognosis when diagnosed early. Existing breast cancer diagnosis devices are mammography, breast ultrasound, breast MRI scan and breast biopsy. But the gold standard for the diagnosis of bre [....] » Read More
Title : MicroRNAs in the composition of platelet- Rich fibrin
Indre Jasineviciute, Lithuanian University of Health Sciences, Lithuania
Regenerative effectiveness of platelet-rich fibrin has been discussed in previous clinical research, but information about its composition related to cellular and genetic composition is lacking. A three-dimensional fibrin matrix in platelet-rich fibrin attracts and traps signific [....] » Read More
Title : Ultra-high throughput multiphoton 3D bio-printer
Linas Jonusauskas, Vital3D Technologies, Lithuania
Fast development in the field of 3D bio-printing showed immense promise in the capability to produce fully functional organs for in vitro testing or even in vivo implantation. However, while there is an abundance of methodologies that can be employed in this role, the challenge o [....] » Read More
Title : Ocular surface regeneration; current strategies and the considerable candidates.
Sara Aghazadeh, Aalborg University, Denmark
The ocular surface comprises the cornea, the outermost layer of the eye. As it is exposed, genetic and environmental factors can affect it and cause permanent deficiencies. Limbal stem cells (LSCs), reside in the basal layer of the epithelium and regenerate the ocular surface. An [....] » Read More
Title : Control release of dexamethasone from 3D printed scaffolds promotes M2 like Macrophage and enhanced Osteogenic Differentiation of MSCs
Majed Majrashi, University of Nottingham, United Kingdom
The immune system plays a vital role in inducing inflammation, tissue repairing and regeneration. Currently, there is an endeavour to investigate the role of macrophages in bone tissue regeneration. It has been elucidated that macrophages can polarise to proinflammatory M1 and an [....] » Read More