All stakeholders involved in the drug manufacturing and distribution process, from raw materials to patients, compose the pharmaceutical supply chain. The pharmaceutical supply chain has its own set of problems to deal with. Pharmaceutical industries must handle the most prevalent issues in the pharmaceutical supply chain in order to get patients their needed pharmaceuticals as quickly as possible. Manufacturers, wholesale distributors, and pharmacy benefit managers are among the many parties involved in the pharmaceutical supply chain (PBM). Pharmaceutical companies have a lot of impact on this complicated process.