Vaccines are undoubtedly the most important medical technology ever discovered, and since Edward Jenner first tested his smallpox vaccine in 1798, they have resulted in substantial decreases in disease morbidity and mortality. Vaccines have traditionally been made by isolating an infectious pathogen, weakening or inactivating it, and then administering it to face the human immune system. More complex vaccine development strategies have both advantages and disadvantages. Most importantly, they provide a way forward in areas where traditional approaches have failed.
The area of vaccination continues to evolve at a breakneck pace, with more effective and acceptable novel vectors and techniques making their way into clinical use. Along with the advancement of these new rationally designed vaccines, improved and more patient-acceptable delivery mechanisms are being developed to better target and sustain the pain-free injection of antigen. Because the majority of vaccines are still delivered with a hypodermic needle, either intramuscularly, subcutaneously, or intradermally, delivery is critical.
Title : Extracellular vesicles as delivery vehicles of therapeutic compounds
Stefania Raimondo, University of Palermo, Italy
Title : EU GMP annex1 barrier system and PIC/s annex 2A on cell and gene therapy
Richard Denk, SKAN AG, Switzerland
Title : Role of nanoformulations in treating Cystic Fibrosis
Bhupendra Gopalbhai Prajapati, Ganpat University, India
Title : Dual GIP/GLP-1 receptor stimulation in treatment of type 2 diabetes mellitus – The ground-breaking 'twincretin' approach
Miroslav Radenkovic, University of Belgrade, Serbia
Title : Pathology and patient safety: The vital role of electronic medical record and pathology informatics in error reduction and precision medicine
Consolato M Sergi, Universities of Alberta and Ottawa, Canada
Title : mRNA-based systemically delivered directed gene therapy using nanomaterials
A C Matin, Stanford University, United States
Title : Colon-specific scallop hydrolysates/Κ-carrageenan hydrogel loaded with curcumin alleviates dss-induced colitis through modulation of inflammatory cytokines and gut microbiota
Hai Tao Wu, Dalian Polytechnic University, China
Title : Mucoadhesive electrospun fibrous systems for the fast and sustained delivery of drugs
Luis Jesus Villarreal Gomez, Autonomous University of Baja California, Mexico
Title : General and local anaesthetic agents: An analysis of their safety data
Francesca Gargano, Campus Bio-Medico University of Rome, Italy
Title : 15,16-dihydrotanshinone-I-laden PLGA-co-PEG nanoparticles are potential therapeutic agents for the treatment of colorectal cancer by targeting the β-catenin/CD36 axis
Kwan Hiu Yee, Hong Kong Baptist University, China