Title : Vitamin D supplementation and loss visceral adiposity in individuals underwent bariatric surgery
The prevalence of obesity is growing exponentially worldwide, and current projections predict that more than 1 billion individuals will have obesity by 2030. The distribution of body fat is an important aspect to assess risks in the development of obesity-related metabolic dysfunction
The body mass index (BMI) is the most used tool in clinical practice; however, it is characterized by low precision and low sensitivity and there is a large inter-individual variability.
Thus, additional body composition assessment parameters should be used to assess the increase in the accumulation of visceral adipose tissue (VAT) in obesity, once VAT inflammation is associated with development of obesity-related metabolic disorders, such as systemic insulin resistance, type 2 diabetes mellitus, and metabolic associated fatty liver disease, and evidence suggests that it may play a critical role in this scenario. In people with obesity, the presence of nutritional deficiencies is common. Vitamin D (VD) has a strongly established relationship with fat distribution and appears to play a peculiar role in the regulation of numerous metabolic processes.
Bariatric surgery may be the most efficacious intervention for losing the excess of body weight and prevention/remission of the associated metabolic disorders. The speech aims to evaluate the relationship between serum concentrations of 25- hydroxyvitamin D (25(OH)D) and the reduction of body fat, especially the compartments in which fat is located, considering the nutritional status of VD in individuals with obesity undergoing the Roux-en-Y gastric bypass (RYGB), after 12 months of follow-up using two different vitamin D3 (VD3) supplementation protocols.
Audience Take Away Notes:
• Obesity is related to nutritional deficiencies; one is vitamin D deficiency (VDD).
• VD has a relationship with fat mass and an important role in metabolic processes.
• Fat mass distribution is relevant to assess the development of metabolic dysfunction.