Endogenous biomarkers are compounds naturally produced within the body that reflect health status, physiological processes, or disease progression. Examples include glucose, cholesterol, and specific hormones that provide insight into metabolic health. In nutrition research, these biomarkers are used to assess the body’s response to dietary changes, helping determine the effectiveness of interventions. For instance, blood glucose levels help evaluate the impact of dietary changes on diabetes management, while lipid profiles reveal effects on cardiovascular risk. Research into endogenous biomarkers aids in understanding how nutrients and dietary patterns influence the body’s physiology, enabling more targeted dietary recommendations for disease prevention and management.