Tissue chips are engineered microsystems that represent units of human organs like the lung, liver and heart modeling both structure and performance. The chips merge techniques from the pc industry with modern tissue engineering to mix miniature models of living organ tissues on a transparent microchip. It is to develop bioengineered devices to enhance the method of predicting whether drugs are going to be safe or toxic in humans.
During human clinical trials, approximately 90 percent of candidate drugs fail because they are unsafe (~30% ) or ineffective (~60 %). Even when pre-clinical cell and animal studies seem promising, problems occur because drugs tested with these models often don't have an equivalent response in humans.
Title : AI-integrated high-throughput tissue-chip for space-based biomanufacturing applications
Kunal Mitra, Florida Tech, United States
Title : Will be updated soon...
Vasiliki E Kalodimou, European University-Cyprus Ltd, Cyprus
Title : Will be updated soon...
Nagy Habib, Imperial College London, United Kingdom
Title : Will be updated soon...
Alexander Seifalian, Nanotechnology & Regenerative Medicine Commercialisation Centre, United Kingdom
Title : Advanced 3D tissue models: Pioneering tools for investigating health and disease
Lucie Bacakova, Institute of Physiology of the Czech Academy of Sciences, Czech Republic
Title : Developing iPSC-derived 3D Outer Blood-Retinal Barrier Disease Models of Choroideremia for Gene Therapy Evaluation
Aradhana Kasimsetty, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), United States