Tissue Chip for Drug Screening

• Bio-Chips
• Microelectronics
• Microfabrication and Microfluidics

Tissue chips are engineered microsystems that represent units of human organs like the lung, liver and heart modeling both structure and performance. The chips merge techniques from the pc industry with modern tissue engineering to mix miniature models of living organ tissues on a transparent microchip. It is to develop bioengineered devices to enhance the method of predicting whether drugs are going to be safe or toxic in humans.

During human clinical trials, approximately 90 percent of candidate drugs fail because they are unsafe (~30% ) or ineffective (~60 %). Even when pre-clinical cell and animal studies seem promising, problems occur because drugs tested with these models often don't have an equivalent response in humans.